December 2018

Dear Friend: We wanted to give you an update on the extremely important and successful work that the Institute for Myeloma & Bone Cancer Research (IMBCR) has conducted during the past six months as we continue our groundbreaking research into finding a cure for multiple myeloma and other bone cancers. IMBCR remains the only independent…

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Research Update July 2018

Dear Friend: We wanted to give you an update on the extremely important and successful work that the Institute for Myeloma & Bone Cancer Research (IMBCR) has undertaken during the past six months as we continue our groundbreaking research into finding a cure for multiple myeloma and other bone cancers. IMBCR remains the only independent…

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smile.amazon.com

If you’re an Amazon customer, it’s easy to donate to IMBCR automatically, with almost every purchase. Just go to www.smile.amazon.com and follow 2 simple steps. STEP 1: Go to www.smile.amazon.com and enter “Institute for Myeloma & Bone Cancer Research” (NOT imbcr.org) into the “Search for your charity” box. STEP 2: When our name pops up…

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Anti-angiogenic and anti-multiple myeloma effects of oprozomib (OPZ) alone and in combination with pomalidomide (Pom) and/or dexamethasone (Dex)

Sanchez E, Li M, Wang CS, Tang G, Gillespie A, Chen H, Berenson JR Abstract Oprozomib (OPZ or ONYX 0912) is an irreversible, orally administered proteasome inhibitor (PI) and an analog of carfilzomib. We set out to determine the anti-angiogenic effect of OPZ using the choriollantoic membrane/feather bud (CAM/FB) model and its anti-MM effects using…

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Outcomes of Multiple Myeloma Patients Receiving Bortezomib, Lenalidomide and Carfilzomib

Berenson A, Vardanyan S, David M, Wang J, Harutyunyan NM, Gottlieb J, Halleluyan R, Spektor TM, Udd KA Eshaghian S, Nassir Y, Eades B, Swift R, Berenson JR Abstract New classes of drugs including the proteasome inhibitors (PI) bortezomib and, more recently, carfilzomib and the immunomodulatory agent lenalidomide have shown improved outcomes for multiple myeloma…

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